![]() ![]() In addition, the use of CGM in T1DM is continuously expanding due to recent improvements in the accuracy and period of use of the sensor and the expansion of the national reimbursement policy ( 11). In various diabetes guidelines, the use of CGM is suggested as a standard treatment for the management of T1DM ( 9, 10). Studies have demonstrated that the use of CGM improved glycemic control in patients with type 1 diabetes mellitus (T1DM) using daily insulin injection ( 5– 8). The main CGM metrics including time in range (TIR), time below range (TBR), and time above range (TAR) inform more personalized glycemic profiles compared with HbA1c ( 4). Continuous glucose monitoring (CGM) demonstrates a continuous measurement of glucose levels over time and detects glucose variations with CGM metrics ( 3). Hemoglobin A1c (HbA1c) has been the gold standard marker for assessing glycemic status and predicting diabetes complications, but it provides limited information that cannot reflect glycemic variability and the presence of severe hypoglycemia or hyperglycemia ( 1, 2). In the continuous glucose monitoring user group, those who achieved more than 70% of time in range significantly increased from 3 months (37.4%) to 12 months (48.2%) ( P < 0.001).Ĭonclusion: In this longitudinal study of type 1 diabetes mellitus adults, the use of continuous glucose monitoring for 1 year showed a significant reduction in glycated A1c in real-world practice. ![]() A linear mixed model showed an adjusted treatment group difference in mean reduction in glycated A1c of −0.11% (95% confidence interval, −0.16 to −0.06) each three months. Changes in glycated A1c were significant at 3, 6, 9, and 12 months compared with those at baseline in patients using continuous glucose monitoring ( P < 0.001), and the changes differed significantly between the groups ( P < 0.001). Results: The change in glycated A1c from baseline to 12 months was −0.5% ± 1.0% for the continuous glucose monitoring user group ( N = 155, P < 0.001) and −0.01% ± 1.0% for the non-user group ( N = 310, P = 0.816), with a significant difference between the two groups ( P = 0.003). We used the linear mixed models to identify the quantitative reduction in repeated measures of glycated A1c. Individuals with ( N = 155) or without continuous glucose monitoring use ( N = 310) were matched 1:2 by propensity score. Glycated A1c was measured at baseline and 3, 6, 9, and 12 months. Methods: We included type 1 diabetes mellitus adults who were either new continuous glucose monitoring users ( N = 155) or non-users who were under standard care ( N = 384). 2Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of KoreaĪim: We explored the effectiveness of continuous glucose monitoring for 1 year on glycated A1c reduction in adults with type 1 diabetes mellitus.1Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.So Hyun Cho 1† Seohyun Kim 2† You-Bin Lee 1 Sang-Man Jin 1 Kyu Yeon Hur 1 Gyuri Kim 1* Jae Hyeon Kim 1,2*
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![]() The love story by itself would be exciting. It is masterful filmmaking, The thriller elements alone would command our attention. In the whole middle section of this movie, he shows the man from the city and the simple Amish women within the context of the Amish community. "Witness" was directed by Peter Weir, the gifted Australian director of " The Year of Living Dangerously." He has a strong and sure feeling for places, for the land, for the way that people build their self-regard by the way they do their work. It's about two independent, complicated people who begin to love each other because they have shared danger, they work well together, they respect each other - and because their physical attraction for each other is so strong it almost becomes another character in the movie. It's not one of those romances where the man and woman fall into each other's arms because their hormones are programmed that way. Now it turns into an intelligent and perceptive love story. Up until the return to Pennsylvania, "Witness" has been a slick, superior thriller. He manages to drive them all back to the Amish lands of Pennsylvania before collapsing from loss of blood.Īnd it's at this point, really, that the movie begins. ![]() His life and the lives of the widow and her son are in immediate danger. Then it turns out that the police department itself is implicated in the killing. He stages lineups hoping the kid can spot the murderer. Harrison Ford plays the tough big city detective who gets assigned to the case. In the train station in Philadelphia, the little boy witnesses a murder. His widow and young son leave on a train journey. ![]() Deivamani, Assistant Professor, Horticulture Research Station, Yercaud-636602. ![]() Close plant spacing and over-irrigation promote disease development and should be avoidedĭr.Southern blight has a wide host range, affecting over 500 plant species. and can even cause problems in temperate locations like Wisconsin during periods of warm, moist weather. This disease causes damage in the southern U.S. Crop rotations of two years or more to a non-host crop like corn or small grains will help to prevent build-up of inoculum and disease problems What is Southern blight Southern blight is a lethal fungal disease that is most common in the tropics and subtropics.Wet periods of high temperatures (85-95 ☏).Soil borne, machinery or water-moved infested soil, survives on numerous weed and crop hosts.In the case of both bacterial wilt and southern blight, unfortunately, there isn’t much that can be done for the current crop of tomatoes once you have the disease. Southern blight can affect many other types vegetable plants, including peppers, green beans, and watermelons. Slightly sunken, yellow spots develop on invaded fruit, which rapidly decay, collapse, and become covered by a white fungal mass with numerous sclerotia. As with bacterial wilt, tomato is not the only host of this disease.The use of rhizobacteria for the biological control of Southern blight disease is a potent alternative to chemical fungicides. Fungus is exceedingly destructive on ground crops and attacks the fruit where they contact the soil. Southern blight of tomato caused by Sclerotium rolfsii can cause severe plant mortality and yield losses.It has been a significant crop pest in warmer parts of the. Often the entire root system is destroyed. It was named for a Peter Henry Rolfs, who first found it in tomato fields in Florida in 1892.Mycelium often grows over the diseased tissue and surrounding soil forming a white mat of mycelial threads with the typical tan-to brown, at the crown mustard-seed-sized sclerotia.Mature plants are attacked just below the soil surface and are completely girdled.Post Harvest Diseases:: Vegetables:: Tomato Furthermore, it can process video in the background without interfering in the workflow. Greater performance with 64-bit architectures and a better use of the Mac's GPU.It allows us to edit metadata and keywords to mark intervals and integrate them into smart collections. A library-based content organization with automatic content analysis.Video editing with advanced organization functions that provide a faster workflow adapted to the user.It offers us a wide range of complete functions: All these qualities have been boosted by a complete redesign that has optimized the organization of contents on the interface and improved the program's global performance.Īmongst the five best video editors on computer. Its users appreciate this software due to its speed when it comes to editing and mounting videos, its wide range of tools, the quality of the final result, and the fact that it's compatible with third-party plug-ins. ![]() A reference for professional video editors Developed by Apple, and only available for Mac, it's one of the most powerful and versatile video editing programs on the market. ![]() But when it comes to choosing the three or four best video editors for computers, we're sure that there's a name that will appear on all the lists: Final Cut Pro X. It's hard to say which is the best video editor of them all because we're talking about complex tools at a professional level, in which each user ends up specializing in certain ones and their yield depends directly on the control of each user. ![]() We're here to help with technical issues, not market for others.ġ2: No spam, trolling, insults, jokes, threats of self-harm, or posts unrelated to Tech Support This includes (but is not limited to) asking for us to link to your subreddit, forum, bulletin board, newsgroup, Facebook page, etc. Approach the communities affected directly, not here No public service announcements unless relevant to an issue (it must be a comment). We will also not assist with getting Windows 11 running on unsupported hardware.ġ0: No Public Service Announcements (how-to's, etc.) This list includes Windows XP, Vista, and 7. Running them is unsafe and we recommend users install a supported version as soon as possible. These operating systems and various softwares are no longer receiving security patches. Software that is EOL has lost all support from the developer and therefore all consumer communities as well. We do not provide support for EOL (end of life) software. Doing so might resolve in a ban.Īny other posts/comments that violates or breaks terms and agreements.ĩ: No EOL Software or Unsupported Systems We do not support users that violates other's privacy or breaks terms and agreements. Doing so will cause you to be permanently banned from /r/TechSupport.Ĩ: No Violating privacy of others or terms/agreements. Private messages and other services are unsafe as they cannot be monitored. No posts about jobs (tech support related or not) or technology in general, such as "I have an interview, help me." or "I want a product that can do XYZ." or "How does the internet work?"ħ: No Private Messages or Moving to Another ServiceĪny and all communication not kept public and is moved away from the subreddit or Discord/IRC channel is prohibited.ĭo not suggest or ask to move to another service or to private message. If you want anything added please message the mods and we will consider it. Recommending products not in the whitelist might result in your comment or post being removed and a ban imposed. Recommending a hardware/software solution as a comment to a post is acceptable. We do not allow posts asking for recommendations on hardware/software or recommendations comparing two or more hardware/software. We are not a recommendation or advertisement subreddit. ![]() ![]() Please do not take advantage of the community. This community is "free" as it is full of volunteers. No Amazon gift voucher or PayPal transfer. No offering of reward/compensation for solutions. Issues with account lockout on any of the above platforms (and all others) Google, Apple, Microsoft, Instagram, Facebook or any other account Password Only support for the related account can help you. Do not message us asking us to make an exception. We cannot assist with password or account issues. Please make your title and contents descriptive. ![]() Posts with "Help" or non-descriptive titles. Posts with an empty body, only a link in the body, title copied into the body, and/or lack of information in the body Submissions consisting of the following are considered incomplete and will be removed: Please read our new rules page for more in-depth rules. Please do not submit the same issue more than once within 24 hours. Do everything you can to reduce the effort of the wonderful folks offering to help you.Īfter solving your problem, please mark it as solved by clicking 'flair' and confirming the 'solved' tag. State everything you have tried and all the guides/tutorials/sites you have followed as well as why they were unsuccessful. Try to research your issue before posting, don't be vague. The subreddit is only for support with tech issues. Please include your system specs, such as Windows/Linux/Mac version/build, model numbers, troubleshooting steps, symptoms, etc. Live Chat ~Enter Discord~ Submission Guidelines Check out our Knowledge Base, all guides are compiled by our Trusted Techs. įactors which have been proven to increase embolic risk are increased catheter time in the left atrium (LA), chronicity of AF, activated clotting time (ACT) below 250 seconds, duration of individual ablations, larger LA size, non-irrigated ablation and the presence of spontaneous echo contrast. The possible embolic sources are thrombus formation on the ablation electrode and sheath, debris from steam popping and charring, preexisting thrombus in the cardiac chamber, air embolus from within the sheath and fresh thrombus formed on damaged endothelial surface of endocardial lesions,. Therapeutic periprocedural anticoagulation significantly reduced ACL. The presence of spontaneous echo contrast and procedural duration before heparin administration were determinants of ACL. found 13–20% prevalence of cognitive dysfunction at three months in AF patients treated with ablation compared to none in those managed medically. An even higher incidence of 41% was reported by the MACAP study when more sensitive 3 Tesla MRI imaging was performed. Asymptomatic cerebral lesion (ACL) was common ranging from 10 to 14%. However, there is ample evidence to suggest that the subclinical cerebral embolism during left sided ablations especially pulmonary venous isolation (PVI) for AF is far more common. The reported incidence of clinical stroke in AF ablation is much less than 1%. Animal studies, in vitro studies, conference proceedings, case reports, comments, and surgical ablation articles were excluded. Prospective and retrospective designs, and review articles were included. Out of 5390 articles obtained through this search, 315 journal articles pertaining to safety issues of RF ablation were carefully studied for the review. ![]() Search terms namely radiofrequency ablation, safety, complications, AF, atrio ventricular reentry tachycardia (AVRT), atrio ventricular nodal reentry tachycardia (AVNRT), VT and atrial flutter (A Fl) were used separately and in combination. ![]() Pulmonary vein isolation (PVI) for AF ablation for SVT and VT ablation.Įlectronic database was searched for relevant articles from 1990 to 2015. For the purposes of this review we will consider three broad types of procedures. However the incidence of some chronic complications has risen, as procedures became more complex and time consuming.Ĭatheter ablation procedures are used to treat a diverse range of arrhythmias with vastly different natural histories and alternative treatment options. Even though procedure-related acute complications are on the decline by virtue of better knowledge of arrhythmia physiology, experience of particular group with RF ablation and advancements in technology like mapping, cryoablation and newer ablation techniques such as magnetic navigation. Achieving the optimal balance between efficacy and safety has proven to be challenging. RF ablation has been part of clinical practice for more than two decades and has become an important treatment option for most clinically relevant cardiac arrhythmias. Recent reports about the high incidence of asymptomatic cerebral embolism during AF ablation are concerning, warranting more research into its etiology and prevention. Up to 3% mortality and similar rates of tamponade were reported in endocardial VT ablation. Vascular and pericardial complications dominated endocardial and epicardial VT ablations respectively. In VT ablation the incidence of major complications was 5–11%, up to 3.4%, up to 1.8% and 4.1–8.8% in patients with structural heart disease, without structural heart disease, prophylactic ablations and epicardial ablations respectively. Safety of SVT ablation has also improved with less than 1% incidence of AV node injury in AVNRT ablation. In AF ablation it has decreased from 6% to less than 4% comprising of vascular complications, cardiac tamponade, stroke, phrenic nerve injury, pulmonary vein stenosis, atrio-esophageal fistula (AEF) and death. With better awareness and technological advancements in RF ablation the incidence of complications has improved considerably. Electronic database was searched for relevant articles from 1990 to 2015. Here we look at the various complications of RF ablation and also the methods to minimize them. This might increase the number of procedures performed. ![]() ![]() Evidence is emerging for the probable role of prophylactic ischemic scar ablation to prevent VT. Serious complications do occur during supraventricular tachycardia (SVT) ablations and knowledge of their incidence is important when deciding whether to proceed with ablation. In light of recent reports showing high incidence of silent cerebral infarcts and organized atrial arrhythmias following radiofrequency (RF) atrial fibrillation (AF) ablation, a review of its safety aspects is timely. ![]() Two review authors (KM and JD) independently reviewed each paper for inclusion according to the predefined inclusion criteria, rated the study quality and then extracted relevant data. The titles and abstracts of all search results were screened by two authors (KM and JD) and full manuscripts for all potential relevant papers were obtained. We selected studies in a two-stage process. The aim of this review was to identify the techniques used to diagnose fractures using a tuning fork and assess all studies of the diagnostic accuracy of tuning fork tests for the presence of fracture. Using a stethoscope to listen to the sound over a bony prominence proximal to the fracture site, the fracture is detected by a reduction in the sound conducted along the bone compared to the unaffected limb. The second method uses a vibrating tuning fork placed over a bony prominence distal to the fracture site. ![]() 2 The pain stops or decreases with the removal of the tuning fork. Because the periosteum is heavily innervated, mechanical vibration over a fracture site stimulates the overlying periosteum, causing pain. The first method uses a vibrating tuning fork placed directly over, or closely proximal to the suspected fracture site. ![]() Two methods of using tuning forks to detect fracture(s) have been developed. One test which was proposed at least 60 years ago is the use of a tuning fork. Other clinical tests for fracture may then assist in decision making. Although imaging for suspected fractures is generally cheap and readily accessible, there are situations such as remote settings, where imaging is not readily available. ![]() The Gimp, a minor character in Quentin Tarantino’s iconic film Pulp Fiction, has long been a source of contention. The Gimp: Unintended Victim Of Pulp Fiction Winston Wolf, Harvey Keitel’s character on the show, assisted Jules and Vincent in cleaning up a bloody car. Tarantino explains in the film that the two men shake hands before hugging each other. In Pulp Fiction, Butch saved Marsellus’s life by shielding him from harm, so that if he did not tell anyone what happened, he could still survive. Deliverance, a Burt Reynolds film about hillbilly rape, is set in 1972 Pulp, a 1947 film noir about a boxer, was set in 1947. According to Tarantino, it was an attempt to keep the audience from being overwhelmed. Pulp was accused of playing cheap postmodern games with its genre-shuffling. The film debuted at the 1994 CANNES Film Festival, directed by Quentin Tarantino. Pawnshop scenes from Pulp Fiction have become a modern classic as a result of its popularity. While his exact purpose in the film is never made clear, it appears he exists solely to create an atmosphere of suspense and menace. He is there to punish the robbers who have broken into the shop, and is later seen in the background of a scene where Vincent and Jules are talking. While he is never explicitly identified, it is heavily implied he is a sex slave belonging to Maynard and Zed. He is shown in the basement of Maynard and Zed’s pawn shop wearing a mask, a leather outfit, and chains. The Gimp in Pulp Fiction is a mysterious figure. What Was Up With The Gimp In Pulp Fiction? Hugh Jackman’s character, Wolverine, is incomplete without him. In ways that you couldn’t imagine, Keanu Reeves can inhibit roles in the same way that he can. Jason Statham made his acting debut in the iconic action role of The Transporter in 2002. ![]() We’ll give you a list of seven black-suited movie appearances. Because of their black suits and ties, the actors on the film have created a powerful presence that has left a lasting impression. When it comes to movies starring mafia bosses or secret agents, there is nothing quite like the black suit. Ultimately, the black suit serves as a reminder of Vincent’s journey and his ultimate redemption. In addition, the suit may have been a stylistic choice, paying homage to the film noir genre and its classic style. But why did the filmmakers choose to dress Vincent in a black suit? While there is no definitive answer, there is speculation that the choice was symbolic of Vincent’s struggle to fit in and find his place in the world. In summary, being a gimp is the most strenuous, physically-demanding submissive BDSM role that someone can experience, and the capacity to endure sweat, bondage, penetration, sensory-deprivation, physical labour, being used as furniture, and pain are attributes that make the top gimps renowned for their abilities.The iconic black suit worn by John Travolta‘s character, Vincent Vega, in the 1994 cult classic film, Pulp Fiction, is an enduring image of the movie. It just makes it more exciting for the wearer. Gimps often have a sexual fetish for latex or leather, which helps the gimp to endure the discomfort and restriction of being in the gimp suit, but this fetish is not a requirement to be a gimp. Sex Toy - A gimp should always be prepared to be used as a sex toy – all gimp orifices are simply holes to be filled by the Dominant in whatever manner He or She chooses* Storage - When not in use, gimps are often stored away in a cage or box until it is time to "bring out the gimp" (immortalized in this classic scene from the movie Pulp Fiction) Silence - Gimps should remain quiet unless their Dominant requires them to speak (a gag is often used to prevent noisy gimps from being heard) Suffering - Gimps are born to suffer and should offer their pain and discomfort to their Dominant as a gift to the Divine Service - Gimps should always be of service and provide utility to their Dominant Gimps exist as servants, playthings and recipients of torment for their Dominant and must adhere to the 5 S's of Gimpitude: Harnesses, gags, posture collars and other restrictive gear is often used to further objectify and subdue the gimp for his or her Mistress or Master.Ī convenient phrase to understand the role of the gimp in BDSM is that all gimps are submissive, but not all submissives are gimps. A gimp can best be described as a sexual submissive who is dressed in a rubber or leather suit that covers the entire body, including the hands and head. ![]() Managing your Focused Inboxįocused Inbox intelligently presorts your emails, placing your most important messages in Focused and the rest in Other. When you’re done viewing these welcome screens, tap the white check mark at bottom right to proceed. Once you’re all done, you’ll see a series of welcome screens introducing Focused Inbox, Calendar and Search - all of which are covered in this article.
![]() First and foremost, there are the 10 best racers in the city that are put in a list of the “Most Wanted”. In here, it’s normal to see wild police chases, intense races and more action than you’ll ever see outside the city.īut in order to be recognized as the very best, you’re going to overcome a lot of challenges. In this game, the game is set in the city of Fairhaven which is the place where the biggest racers come together for adrenaline-pumping action. With such a popular series title behind the game, it’s difficult not to see this game taking off. Released in 2012 for mobile gaming, Need for Speed Most Wanted has now over 1 million downloads in Google Play alone. But for the sake of this article, we’re going to talk all about it! Ready to experience the race of your lifetime? Buckle up! One of the Best Racing Games Ever Normally, this wouldn’t need an introduction or an article like this since it’s such a popular title. In this article, we’re going to take a look at one of the most popular games from EA – Need for Speed Most Wanted APK. And when you say racing games, it’s hard not to associate it with the Need for Speed series. It’s one of the pioneer genres that were used for games back then. You can simply drive them by making them just according to your own taste and liking.The racing games genre has been around for ages. In Need for Speed Most Wanted Apk you do not need to do any kind of hard work or play with the basic cars but instead you will be playing with the best brand cars. You will get limitless points in the modified version of the game. You will get many free unlimited cars in this awesome mod version of the game. You will be able to enjoy using this application because the most speed points that you will get upon racing. You will get lots of speed points and can get many cars easily. You can freely customise over 40 plus cars and can drive them easily because in this game play you will be getting so many cars and not just you will be collecting them but instead you will also be able to customize the world famous cars like Porsche. Freely Customize 40 Plus Cars and Drive Them ![]() You have to run from the police so dad you can avoid being chased when you will be causing lots of destruction and violence in the streets then obviously the police will be behind you so that they can arrest you. So the more damage you will cause the more attention you will get and that is the main purpose of playing this game. ![]() You will be doing the damage to cars in this game play and you will never need to worry about destroying the cars because you have to actually create damage and no one will ask you to be accountable for that. Create Violence and Do Car Damage by No Brakes Racing This is a very incredible and outstanding gameplay and once you start playing this game you will find so many unique and new cars that you will be loving for sure. In this game play you will get the best cars and you have to use these premium supercars for playing. Race by Using the Best and Premium Super Cars If you are using a low standard Android version device then the game will just keep on loading and you will not be able to enjoy thoroughly. You will be able to play this 1900 MP game which is just so huge you need to have huge storage and lots of empty space. You can enjoy the heavy and high quality game which is just so incredible. Yes, Need for Speed Most Wanted Apk is for speed points.įeatures Heavy and High Quality Game of 1900 MB Is Need for Speed Most Wanted Apk for speed points? You will get so many supercars and you have to play with them so that you can actually win the game. Yes, Need for Speed Most Wanted Apk is a heavy game of 1900 MBs Can I get cars in Need for Speed Most Wanted Apk? Is Need for Speed Most Wanted Apk a heavy game? You can always play with different cars whenever you use the points. In Need for Speed Most Wanted Mod Apk the game will become much more interesting when you will have many cars available with you. What is Need for Speed Most Wanted Mod Apk? So, keep on playing this massive racing game and have incredible fun here. ![]() In Need for Speed Most Wanted Apk you have to keep on running and make sure that you play smartly in the game so that the police will never be able to catch you and you can enjoy the complete freedom here. In Need for Speed Most Wanted Apk you will be able to get many speed points and then you can use them for getting new cars. You have to make sure that you do not let the police catch you at all, otherwise the game will get over. In Need for Speed Most Wanted Apk if you want to play this game it is a very interesting gameplay with lots of Fantastic features and if you want to play the game perfectly then you need to have a very strong Android device with good quality features so that you can play the game without any kind of lagging. |
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